Emerging Science in Microbiome Market –

Naturally informed, powered by WholeFoods Magazine and Trust Transparency Center, hosted the virtual conference Microbiome: Master the market in May. The second day of the virtual conference focused on emerging science and opportunity. Topics covered ranged from replacement of key lost species, to postbiotics, digestive health, manufacturer practices, and more.

The human microbiome: replacing lost species

To start the second day of the event, in the session, The human microbiome: the power to replace lost species, opening speech speaker William Davis, MD., author of the Wheat Belly series and the new book Super Gut, summed it up by saying, “When you lose healthy species, unhealthy species step in and take their place. These healthy species had important roles. He explained that unhealthy microbes, like E. coli, proliferate without healthy microbes present in the microbiome. This leads to issues such as small intestinal bacterial overgrowth (which he called SEBO), which can contribute to a variety of issues.

What causes the loss of species?

“We have been overexposed to antibiotics, and a third of all children are born by caesarean section, more children are fed formula and [due to] food additives, synthetic sweeteners, [children are] deprived of nutrients and microbes,” Dr. Davis noted. Additionally, the chlorine and fluoride in our drinking water have altered the mucus barrier, the gastrointestinal tract, and the makeup of the human microbiome. Additionally, Dr. Davis pointed to herbicides, pesticides, and the genetic transmission of disrupted microbiomes as causes for the lack of diversity in keystone species today. Also of concern: The problem of lost species is getting worse from generation to generation. Replenishing these microbes can help with weight loss, healthy skin, better sleep, better mood, and more.

How to reconstitute healthy species?

Eating fermented foods like yogurt is a key step. “There are higher counts of microbes in yogurt that has been fermented for 36 hours or more. The real increase in microbes doesn’t occur until hour 30, and so 4 hour fermented yogurt doesn’t have the same effects,” he noted. Supplements can also help. For his recommendation, the full session can be viewed on demand.

More Emerging Microbiome Science

Throughout the day, speakers Alexis Collins, Director of Product & Brand Strategy at Stratum Nutrition, Marvin Singh, MD, Founder and CEO of Precisione Clinic, and Asa Waldstein, Founder and Director of Supplement Advisory Group, also presented. Their sessions covered the topics of postbiotics, nourishment of the microbiome, and regulatory insight into current trends and risks.

WTFs are postbiotics and why should I formulate with them?

In session WTFs are postbiotics and why should I formulate with them?, Collins spoke about the growing popularity of postbiotics with consumers. Google’s search engine for the word increased, “1300% from June 2019 to June 2021.”

But what are postbiotics? “Various terms have been used,” Collins said. “In 2019, the use of the word usage jumped. It was 15 times more used than heat-killed probiotics. It was very trendy. Therefore, the International Scientific Association of Probiotics and Prebiotics (ISAPP) brought together an international group of scientists to discuss what a postbiotic is. Consensus document published by ISAPP: defined as a preparation of inanimate microorganisms and/or their constituents which confers a health benefit on the host. To learn more, watch the full session, which can be viewed on demand.

Panel of practitioners

At the next session, health professionals Lynn O’Connor, MD, director of colon and rectal surgery of New York, section chief of the division of colon and rectal surgery at Mercy Hospital and St. Joseph’s Hospital; Mary Purdy, MS, RDN, integrator and eco-dietician and adjunct lecturer, Bastyr University; and Sara Campbell, Ph.D., FACSM, Associate Professor, Director, Rutgers University, discussed patient misconceptions and innovations, discussed how practitioners focus on the microbiome. Experts combined their understanding of peer-reviewed literature, case studies, research and working with patients. Learn more on demand.

Feed the microbiome

Next, Dr. Singh described how he optimized his health and gut power. “When we talk about good digestive health, what does that mean? This means increasing the diversity of bacterial species in your microbiome, optimizing your risk factor for disease reduction. It is the same as general well-being. Therefore, 70% of our immune system resides in our gut. 90% of serotonin produced in the intestinal tract. The digestive tract is the second brain. In addition, it has its own nervous system. We’re really talking about [trillions of] bacteria and fungi in our digestive tract. Watch the full session.

Regulatory overview

To wrap up the day, Asa Waldstein gave a regulatory overview of current risks in space. “Most enforcement actions are taken because of risky marketing claims. So what is a claim? Anything ending in ‘-itis’, most things ‘-anti’ in the name, everything a medicine is “indicated” for, the name of any disease and make a statement to treat, diagnose, prevent.And there’s more to know: Look online.

All sessions are available for on-demand viewing with free registration here. Event Sponsors AIDP, ClearCut Analytics and SPINS, Enzymedica, NutriScience and Nutrition Stratum made this event free through their commitment to education.

Related: Microbiome Science Highlights: Mastering the Market
Naturally Informed Education: Nootropics
Your Brain on Food: The Gut-Brain Connection

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