CÚRAM researchers this week published an interdisciplinary framework that enables the development of extracellular matrix-inspired hydrogels for biomedical applications.
An extracellular matrix (ECM) is a three-dimensional cementitious material that provides structural support to our cells. Hydrogels mimicking this extracellular matrix (ECM) have become increasingly attractive in biomedical science research due to their tunability and biocompatibility. However, hydrogel development and characterization requires an interdisciplinary approach that is rarely fully realized because it requires an extraordinary degree of researcher skill.
This review is a one-of-a-kind approach that will provide insight into the tools available to properly characterize ECM-based hydrogels and interpret the resulting data. It also provides an accurate roadmap that can be used by biomedical researchers when trying to bridge the gap between materials science and biomedicine.
The summary document was published by Questiona sister journal of Cell and home to multidisciplinary and transformative materials science and impactful research.
Lead author and CÚRAM Director, Professor Abhay Pandit, said: “With this proposed study, we aim to combine knowledge from chemistry, materials science and biology by critically discussing the tools available to properly characterize ECM-based hydrogels and interpreting the resulting data, leading to an accurate roadmap to apply in this exciting field.”
The development and characterization of the ECM hydrogel involves a wide range of interdisciplinary tools; this journal will appeal to chemists, materials scientists, engineers and biologists working in the field. This review provides a concise, comprehensive, and easy-to-follow guide for advanced undergraduates, early postgraduate researchers, industry (MedTech, Pharmaceutical, and BioTech), and experts in this interdisciplinary field.
Professor Pandit further explains: “The impact of this review is an attempt to facilitate further interdisciplinary work to create solutions for chronic diseases in the future, in line with CÚRAM’s mission to improve quality of life. people living with a chronic disease.
It will be a go-to resource for researchers in academia and industry and a source of inspiration for the next generation of materials scientists and engineers. »
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